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A Comparative Pharmacokinetic Study by UHPLC-MS/MS of Main Active Compounds after Oral Administration of Zushima-Gancao Extract in Normal and Adjuvant-Induced Arthritis Rats

A sensitive and rapid ultra high-performance liquid-chromatography tandem mass spectrometry (UHPLC-MS/MS) method has been applied to investigate the influence of rheumatoid arthritis (RA) on the pharmacokinetics of nine analytes (daphnetin, daphnoretin, 7-hydroxycoumarin, liquiritin, isoliquiritin,...

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Detalles Bibliográficos
Autores principales: Shan, Jinjun, Qian, Wenjuan, Peng, Linxiu, Chen, Lianghui, Kang, An, Xie, Tong, Di, Liuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017738/
https://www.ncbi.nlm.nih.gov/pubmed/29361795
http://dx.doi.org/10.3390/molecules23010227