A Cyclic Altered Peptide Analogue Based on Myelin Basic Protein 87–99 Provides Lasting Prophylactic and Therapeutic Protection Against Acute Experimental Autoimmune Encephalomyelitis

In this report, amide-linked cyclic peptide analogues of the 87–99 myelin basic protein (MBP) epitope, a candidate autoantigen in multiple sclerosis (MS), are tested for therapeutic efficacy in experimental autoimmune encephalomyelitis (EAE). Cyclic altered peptide analogues of MBP(87–99) with subst...

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Detalles Bibliográficos
Autores principales: Emmanouil, Mary, Tseveleki, Vivian, Triantafyllakou, Iro, Nteli, Agathi, Tselios, Theodore, Probert, Lesley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017753/
https://www.ncbi.nlm.nih.gov/pubmed/29385090
http://dx.doi.org/10.3390/molecules23020304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017753/
https://www.ncbi.nlm.nih.gov/pubmed/29385090
http://dx.doi.org/10.3390/molecules23020304

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