Cargando…

Synthesis, DNA Binding, and Anticancer Properties of Bis-Naphthalimide Derivatives with Lysine-Modified Polyamine Linkers

A series of bis-naphthalimide derivatives with different diamine linkers were designed and synthesized. All of the synthesized bis-naphthalimide derivatives were characterized by NMR and HRMS spectra. The binding ability between the compounds and CT DNA was evaluated by using UV–Vis titration experi...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Yu, Wu, Chun-Xia, Song, Yu, Huang, Min, Tian, Da-Nian, Yang, Xin-Bin, Fan, Yan-Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017805/
https://www.ncbi.nlm.nih.gov/pubmed/29382135
http://dx.doi.org/10.3390/molecules23020266