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Synthesis, DNA Binding, and Anticancer Properties of Bis-Naphthalimide Derivatives with Lysine-Modified Polyamine Linkers

A series of bis-naphthalimide derivatives with different diamine linkers were designed and synthesized. All of the synthesized bis-naphthalimide derivatives were characterized by NMR and HRMS spectra. The binding ability between the compounds and CT DNA was evaluated by using UV–Vis titration experi...

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Detalles Bibliográficos
Autores principales: Huang, Yu, Wu, Chun-Xia, Song, Yu, Huang, Min, Tian, Da-Nian, Yang, Xin-Bin, Fan, Yan-Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017805/
https://www.ncbi.nlm.nih.gov/pubmed/29382135
http://dx.doi.org/10.3390/molecules23020266

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