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Heterophyllin B Ameliorates Lipopolysaccharide-Induced Inflammation and Oxidative Stress in RAW 264.7 Macrophages by Suppressing the PI3K/Akt Pathways

Heterophyllin B (HB), an active cyclic peptide, is a compound existing in the ethyl acetate extract of Pseudostellaria heterophylla (Miq.) Pax and exhibited the activity of inhibiting the production of NO and cytokines, such as IL-1β and IL-6, in LPS-stimulated RAW 264.7 macrophages. In addition, HB...

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Detalles Bibliográficos
Autores principales: Yang, Chunjing, You, Longtai, Yin, Xingbin, Liu, Yi, Leng, Xin, Wang, Wenping, Sai, Na, Ni, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017815/
https://www.ncbi.nlm.nih.gov/pubmed/29561811
http://dx.doi.org/10.3390/molecules23040717