Antileishmanial Activity of 2-Methoxy-4H-spiro-[naphthalene-1,2′-oxiran]-4-one (Epoxymethoxy-lawsone): A Promising New Drug Candidate for Leishmaniasis Treatment

Epoxymethoxy-lawsone is a naphthoquinone derivative promising as drug candidate for the treatment of leishmaniases. In the present work the effectiveness of epoxymethoxylawsone, and meglumine antimoniate on Leishmania (Leishmania) amazonensis parasites and on mice paw lesions of infected BALB/c mice...

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Detalles Bibliográficos
Autores principales: Oliveira, Luiz Filipe Gonçalves, Souza-Silva, Franklin, de Castro Côrtes, Luzia Monteiro, Cysne-Finkelstein, Lea, de Souza Pereira, Mirian Cláudia, de Oliveira Junior, Francisco Odêncio, Pinho, Rosa Teixeira, Corte Real, Suzana, Bourguignon, Saulo Cabral, Ferreira, Vitor Francisco, Alves, Carlos Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017818/
https://www.ncbi.nlm.nih.gov/pubmed/29642584
http://dx.doi.org/10.3390/molecules23040864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017818/
https://www.ncbi.nlm.nih.gov/pubmed/29642584
http://dx.doi.org/10.3390/molecules23040864

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