The Fungal Metabolite Eurochevalierine, a Sequiterpene Alkaloid, Displays Anti-Cancer Properties through Selective Sirtuin 1/2 Inhibition

NAD(+)-dependent histone deacetylases (sirtuins) are implicated in cellular processes such as proliferation, DNA repair, and apoptosis by regulating gene expression and the functions of numerous proteins. Due to their key role in cells, the discovery of small molecule sirtuin modulators has been of...

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Detalles Bibliográficos
Autores principales: Schnekenburger, Michael, Mathieu, Véronique, Lefranc, Florence, Jang, Jun Young, Masi, Marco, Kijjoa, Anake, Evidente, Antonio, Kim, Hyun-Jung, Kiss, Robert, Dicato, Mario, Han, Byung Woo, Diederich, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017873/
https://www.ncbi.nlm.nih.gov/pubmed/29401749
http://dx.doi.org/10.3390/molecules23020333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017873/
https://www.ncbi.nlm.nih.gov/pubmed/29401749
http://dx.doi.org/10.3390/molecules23020333

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