Cargando…

Synthesis of New C- and N-β-d-Glucopyranosyl Derivatives of Imidazole, 1,2,3-Triazole and Tetrazole, and Their Evaluation as Inhibitors of Glycogen Phosphorylase

The aim of the present study was to broaden the structure-activity relationships of C- and N-β-d-glucopyranosyl azole type inhibitors of glycogen phosphorylase. 1-Aryl-4-β-d-gluco-pyranosyl-1,2,3-triazoles were prepared by copper catalyzed azide-alkyne cycloadditions between O-perbenzylated or O-per...

Descripción completa

Detalles Bibliográficos
Autores principales: Kun, Sándor, Bokor, Éva, Sipos, Ádám, Docsa, Tibor, Somsák, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017874/
https://www.ncbi.nlm.nih.gov/pubmed/29543771
http://dx.doi.org/10.3390/molecules23030666