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Natural Alkaloids and Heterocycles as G-Quadruplex Ligands and Potential Anticancer Agents

G-quadruplexes are four-stranded nucleic acid secondary structures that are formed in guanine-rich sequences. G-quadruplexes are widely distributed in functional regions of the human genome and transcriptome, such as human telomeres, oncogene promoter regions, replication initiation sites, and untra...

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Detalles Bibliográficos
Autores principales: Che, Tong, Wang, Yu-Qing, Huang, Zhou-Li, Tan, Jia-Heng, Huang, Zhi-Shu, Chen, Shuo-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017894/
https://www.ncbi.nlm.nih.gov/pubmed/29473874
http://dx.doi.org/10.3390/molecules23020493