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Natural Alkaloids and Heterocycles as G-Quadruplex Ligands and Potential Anticancer Agents
G-quadruplexes are four-stranded nucleic acid secondary structures that are formed in guanine-rich sequences. G-quadruplexes are widely distributed in functional regions of the human genome and transcriptome, such as human telomeres, oncogene promoter regions, replication initiation sites, and untra...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017894/ https://www.ncbi.nlm.nih.gov/pubmed/29473874 http://dx.doi.org/10.3390/molecules23020493 |