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CpG Methylation Changes G-Quadruplex Structures Derived from Gene Promoters and Interaction with VEGF and SP1

G-quadruplex (G4) is a DNA/RNA conformation that consists of two or more G-tetrads resulting from four-guanine bases connected by Hoogsteen-type hydrogen bonds, which is often found in the telomeres of chromatin, as well as in the promoter regions of genes. The function of G4 in the genomic DNA is b...

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Detalles Bibliográficos
Autores principales: Tsukakoshi, Kaori, Saito, Shiori, Yoshida, Wataru, Goto, Shinichi, Ikebukuro, Kazunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017926/
https://www.ncbi.nlm.nih.gov/pubmed/29670067
http://dx.doi.org/10.3390/molecules23040944