A Novel Synthesis of Highly Functionalized Pyridines by a One-Pot, Three-Component Tandem Reaction of Aldehydes, Malononitrile and N-Alkyl-2-cyanoacetamides under Microwave Irradiation

A convenient, fast and environmentally benign procedure for the synthesis of a new series of highly functionalized N-alkylated pyridines as privileged medicinal scaffolds was developed via a unique three-component reaction of easily available aromatic as well as heteroaromatic aldehydes, N-alkyl-2-c...

Descripción completa

Detalles Bibliográficos
Autores principales: Mekheimer, Ramadan Ahmed, Al-Sheikh, Mariam Abdullah, Medrasi, Hanadi Yousef, Alsofyani, Najla Hosain Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017934/
https://www.ncbi.nlm.nih.gov/pubmed/29522435
http://dx.doi.org/10.3390/molecules23030619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017934/
https://www.ncbi.nlm.nih.gov/pubmed/29522435
http://dx.doi.org/10.3390/molecules23030619

Ejemplares similares