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A Novel Synthesis of Highly Functionalized Pyridines by a One-Pot, Three-Component Tandem Reaction of Aldehydes, Malononitrile and N-Alkyl-2-cyanoacetamides under Microwave Irradiation

A convenient, fast and environmentally benign procedure for the synthesis of a new series of highly functionalized N-alkylated pyridines as privileged medicinal scaffolds was developed via a unique three-component reaction of easily available aromatic as well as heteroaromatic aldehydes, N-alkyl-2-c...

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Detalles Bibliográficos
Autores principales:	Mekheimer, Ramadan Ahmed, Al-Sheikh, Mariam Abdullah, Medrasi, Hanadi Yousef, Alsofyani, Najla Hosain Hassan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017934/ https://www.ncbi.nlm.nih.gov/pubmed/29522435 http://dx.doi.org/10.3390/molecules23030619

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