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Anti-Cancer Activity of Phenyl and Pyrid-2-yl 1,3-Substituted Benzo[1,2,4]triazin-7-ones and Stable Free Radical Precursors

Cell viability studies for benzo[1,2,4]triazin-7-ones and 1,2,4-benzotriazinyl (Blatter-type) radical precursors are described with comparisons made with 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO). All of the stable free radicals were several orders of magnitude less cytotoxic than the benzo[1,2,4...

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Detalles Bibliográficos
Autores principales: Keane, Lee-Ann J., Mirallai, Styliana I., Sweeney, Martin, Carty, Michael P., Zissimou, Georgia A., Berezin, Andrey A., Koutentis, Panayiotis A., Aldabbagh, Fawaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017941/
https://www.ncbi.nlm.nih.gov/pubmed/29510488
http://dx.doi.org/10.3390/molecules23030574