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Synthesis, Anti-Proliferative Activity Evaluation and 3D-QSAR Study of Naphthoquinone Derivatives as Potential Anti-Colorectal Cancer Agents

Colorectal cancer (CRC) is a disease with high incidence and mortality, constituting the fourth most common cause of death from cancer worldwide. Naphthoquinones are attractive compounds due to their biological and structural properties. In this work, 36 naphthoquinone derivatives were synthesized a...

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Detalles Bibliográficos
Autores principales: Acuña, Julio, Piermattey, Jhoan, Caro, Daneiva, Bannwitz, Sven, Barrios, Luis, López, Jairo, Ocampo, Yanet, Vivas-Reyes, Ricardo, Aristizábal, Fabio, Gaitán, Ricardo, Müller, Klaus, Franco, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017957/
https://www.ncbi.nlm.nih.gov/pubmed/29342104
http://dx.doi.org/10.3390/molecules23010186