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PER, a Circadian Clock Component, Mediates the Suppression of MMP-1 Expression in HaCaT Keratinocytes by cAMP

Skin circadian clock system responds to daily changes, thereby regulating skin functions. Exposure of the skin to UV irradiation induces the expression of matrix metalloproteinase-1 (MMP-1) and causes DNA damage. It has been reported both DNA repair and DNA replication are regulated by the circadian...

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Detalles Bibliográficos
Autores principales: Yeom, Miji, Lee, HansongI, Shin, Seoungwoo, Park, Deokhoon, Jung, Eunsun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017963/
https://www.ncbi.nlm.nih.gov/pubmed/29570674
http://dx.doi.org/10.3390/molecules23040745