Quantifying the Interaction between Copper-Zinc Superoxide Dismutase (Sod1) and its Copper Chaperone (Ccs1)

Immature copper-zinc superoxide dismutase (Sod1) is activated by its copper chaperone (Ccs1). Ccs1 delivers a single copper ion and catalyzes oxidation of an intra-subunit disulfide bond within each Sod1 monomer through a mechanistically ambiguous process. Here, we use residue specific fluorescent l...

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Detalles Bibliográficos
Autores principales: Boyd, Stefanie D, Liu, Li, Bulla, Lee, Winkler, Duane D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018003/
https://www.ncbi.nlm.nih.gov/pubmed/29950795
http://dx.doi.org/10.4172/jpb.1000473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018003/
https://www.ncbi.nlm.nih.gov/pubmed/29950795
http://dx.doi.org/10.4172/jpb.1000473

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