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Sirt3 Ameliorates Oxidative Stress and Mitochondrial Dysfunction After Intracerebral Hemorrhage in Diabetic Rats

Aim: Sirtuin3 (sirt3) plays a pivotal role in improving oxidative stress and mitochondrial dysfunction which directly induced neuronal apoptosis after intracerebral hemorrhage (ICH). Reactive oxygen species (ROS) is also a critical activator in triggering NACHT, LRR, and PYD domains-containing prote...

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Detalles Bibliográficos
Autores principales: Zheng, Jingwei, Shi, Ligen, Liang, Feng, Xu, Weilin, Li, Tao, Gao, Liansheng, Sun, Zeyu, Yu, Jun, Zhang, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018086/
https://www.ncbi.nlm.nih.gov/pubmed/29970985
http://dx.doi.org/10.3389/fnins.2018.00414