Full rescue of an inactive olfactory receptor mutant by elimination of an allosteric ligand-gating site

Ligand-gating has recently been proposed as a novel mechanism to regulate olfactory receptor sensitivity. TAAR13c, the zebrafish olfactory receptor activated by the death-associated odor cadaverine, appears to possess an allosteric binding site for cadaverine, which was assumed to block progress of...

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Detalles Bibliográficos
Autores principales: Sharma, Kanika, Balfanz, Sabine, Baumann, Arnd, Korsching, Sigrun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018111/
https://www.ncbi.nlm.nih.gov/pubmed/29941999
http://dx.doi.org/10.1038/s41598-018-27790-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018111/
https://www.ncbi.nlm.nih.gov/pubmed/29941999
http://dx.doi.org/10.1038/s41598-018-27790-7

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