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Full rescue of an inactive olfactory receptor mutant by elimination of an allosteric ligand-gating site
Ligand-gating has recently been proposed as a novel mechanism to regulate olfactory receptor sensitivity. TAAR13c, the zebrafish olfactory receptor activated by the death-associated odor cadaverine, appears to possess an allosteric binding site for cadaverine, which was assumed to block progress of...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018111/ https://www.ncbi.nlm.nih.gov/pubmed/29941999 http://dx.doi.org/10.1038/s41598-018-27790-7 |