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ADAM-like Decysin-1 (ADAMDEC1) is a positive regulator of Epithelial Defense Against Cancer (EDAC) that promotes apical extrusion of RasV12-transformed cells

Recent studies have revealed that newly emerging transformed cells are often eliminated from epithelia via cell competition with the surrounding normal epithelial cells. However, it remains unknown whether and how soluble factors are involved in this cancer preventive phenomenon. By performing stabl...

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Detalles Bibliográficos
Autores principales: Yako, Yuta, Hayashi, Takashi, Takeuchi, Yasuto, Ishibashi, Kojiro, Kasai, Nobuhiro, Sato, Nanami, Kuromiya, Keisuke, Ishikawa, Susumu, Fujita, Yasuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018119/
https://www.ncbi.nlm.nih.gov/pubmed/29941981
http://dx.doi.org/10.1038/s41598-018-27469-z