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Detection of minority drug resistant mutations in Malawian HIV-1 subtype C-positive patients initiating and on first-line antiretroviral therapy

BACKGROUND: Minority drug resistance mutations (DRMs) that are often missed by Sanger sequencing are clinically significant, as they can cause virologic failure in individuals treated with antiretroviral therapy (ART) drugs. OBJECTIVE: This study aimed to estimate the prevalence of minor DRMs among...

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Detalles Bibliográficos
Autores principales: Zhou, Zhiyong, Tang, Kevin, Zhang, Guoqing, Wadonda-Kabondo, Nellie, Moyo, Kundai, Rowe, Lori A., DeVos, Joshua R., Wagar, Nick, Zheng, Du-Ping, Guo, Hongxiong, Nkengasong, John, Frace, Mike, Sammons, Scott, Yang, Chunfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AOSIS 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018132/
https://www.ncbi.nlm.nih.gov/pubmed/29977795
http://dx.doi.org/10.4102/ajlm.v7i1.708