A genome-wide mutation analysis method enabling high-throughput identification of chemical mutagen signatures

Trinucleotide mutational signatures extracted from cancer genomes provide clues useful in understanding the roles of mutagens and mutagenic mechanisms in cancer development. The lack of a simple method for genome-wide analysis of alterations induced by mutagens hampers the identification of trinucle...

Descripción completa

Detalles Bibliográficos
Autores principales: Matsumura, Shoji, Fujita, Yurika, Yamane, Masayuki, Morita, Osamu, Honda, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018237/
https://www.ncbi.nlm.nih.gov/pubmed/29942026
http://dx.doi.org/10.1038/s41598-018-27755-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018237/
https://www.ncbi.nlm.nih.gov/pubmed/29942026
http://dx.doi.org/10.1038/s41598-018-27755-w

Ejemplares similares