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A genome-wide mutation analysis method enabling high-throughput identification of chemical mutagen signatures
Trinucleotide mutational signatures extracted from cancer genomes provide clues useful in understanding the roles of mutagens and mutagenic mechanisms in cancer development. The lack of a simple method for genome-wide analysis of alterations induced by mutagens hampers the identification of trinucle...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018237/ https://www.ncbi.nlm.nih.gov/pubmed/29942026 http://dx.doi.org/10.1038/s41598-018-27755-w |