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Green light-induced apoptosis in cancer cells by a tetrapyridyl ruthenium prodrug offering two trans coordination sites

In this work, two new photopharmacological ruthenium prodrugs are described that can be activated by green light. They are based on the tetrapyridyl biqbpy ligand (6,6′-bis[N-(isoquinolyl)-1-amino]-2,2′-bipyridine), which coordinates to the basal plane of the metal centre and leaves two trans coordi...

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Detalles Bibliográficos
Autores principales: van Rixel, V. H. S., Siewert, B., Hopkins, S. L., Askes, S. H. C., Busemann, A., Siegler, M. A., Bonnet, Sylvestre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018302/
https://www.ncbi.nlm.nih.gov/pubmed/30155140
http://dx.doi.org/10.1039/c6sc00167j