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Green light-induced apoptosis in cancer cells by a tetrapyridyl ruthenium prodrug offering two trans coordination sites
In this work, two new photopharmacological ruthenium prodrugs are described that can be activated by green light. They are based on the tetrapyridyl biqbpy ligand (6,6′-bis[N-(isoquinolyl)-1-amino]-2,2′-bipyridine), which coordinates to the basal plane of the metal centre and leaves two trans coordi...
Autores principales: | van Rixel, V. H. S., Siewert, B., Hopkins, S. L., Askes, S. H. C., Busemann, A., Siegler, M. A., Bonnet, Sylvestre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018302/ https://www.ncbi.nlm.nih.gov/pubmed/30155140 http://dx.doi.org/10.1039/c6sc00167j |
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