Loss of Glis3 causes dysregulation of retrotransposon silencing and germ cell demise in fetal mouse testis

Fetal germ cell development is regulated by an elaborate combination of cell-extrinsic and cell-intrinsic signals. Here we identify a novel role for the Krüppel-like transcription factor Gli-Similar 3 (Glis3) in male germ cell development in the mouse embryos. Glis3 is expressed in male germ cells d...

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Detalles Bibliográficos
Autores principales: Ungewitter, Erica K., Rotgers, Emmi, Kang, Hong Soon, Lichti-Kaiser, Kristin, Li, Leping, Grimm, Sara A., Jetten, Anton M., Yao, Humphrey H.-C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018429/
https://www.ncbi.nlm.nih.gov/pubmed/29941866
http://dx.doi.org/10.1038/s41598-018-27843-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018429/
https://www.ncbi.nlm.nih.gov/pubmed/29941866
http://dx.doi.org/10.1038/s41598-018-27843-x

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