Ultrasensitive detection of telomerase activity in a single cell using stem-loop primer-mediated exponential amplification (SPEA) with near zero nonspecific signal

Telomerase is a crucial biomarker for cancers. Its reliable and sensitive detection, particularly in a single cell, has great significance for the early diagnosis of cancers, studies on tumor progression and anticancer therapy, which remain a challenge, due to nonspecific amplification. Herein, we d...

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Detalles Bibliográficos
Autores principales: Wang, Honghong, Wang, Hui, Liu, Chenghui, Duan, Xinrui, Li, Zhengping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018513/
https://www.ncbi.nlm.nih.gov/pubmed/30155143
http://dx.doi.org/10.1039/c6sc00802j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018513/
https://www.ncbi.nlm.nih.gov/pubmed/30155143
http://dx.doi.org/10.1039/c6sc00802j

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