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Ultrasensitive detection of telomerase activity in a single cell using stem-loop primer-mediated exponential amplification (SPEA) with near zero nonspecific signal
Telomerase is a crucial biomarker for cancers. Its reliable and sensitive detection, particularly in a single cell, has great significance for the early diagnosis of cancers, studies on tumor progression and anticancer therapy, which remain a challenge, due to nonspecific amplification. Herein, we d...
Autores principales: | Wang, Honghong, Wang, Hui, Liu, Chenghui, Duan, Xinrui, Li, Zhengping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018513/ https://www.ncbi.nlm.nih.gov/pubmed/30155143 http://dx.doi.org/10.1039/c6sc00802j |
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