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The Role of Semaphorin 4D in Bone Remodeling and Cancer Metastasis

Semaphorin 4D (Sema4D; CD100) is a transmembrane homodimer 150-kDa glycoprotein member of the Semaphorin family. Semaphorins were first identified as chemorepellants that guide neural axon growth. Sema4D also possesses immune regulatory activity. Recent data suggest other Sema4D functions: inactivat...

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Detalles Bibliográficos
Autores principales: Lontos, Konstantinos, Adamik, Juraj, Tsagianni, Anastasia, Galson, Deborah L., Chirgwin, John M., Suvannasankha, Attaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018527/
https://www.ncbi.nlm.nih.gov/pubmed/29971044
http://dx.doi.org/10.3389/fendo.2018.00322