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The multifaceted allosteric regulation of Aurora kinase A

The protein kinase Aurora A (AurA) is essential for the formation of bipolar mitotic spindles in all eukaryotic organisms. During spindle assembly, AurA is activated through two different pathways operating at centrosomes and on spindle microtubules. Recent studies have revealed that these pathways...

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Detalles Bibliográficos
Autor principal: Levinson, Nicholas Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018539/
https://www.ncbi.nlm.nih.gov/pubmed/29946042
http://dx.doi.org/10.1042/BCJ20170771