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Ischaemic Preconditioning Protects Cardiomyocytes from Anthracycline-Induced Toxicity via the PI3K Pathway

PURPOSE: Anthracyclines cause chronic irreversible cardiac failure, but the mechanism remains poorly understood. Emerging data indicate that cardiac damage begins early, suggesting protective modalities delivered in the acute stage may confer prolonged benefit. Ischaemic preconditioning (IPC) activa...

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Detalles Bibliográficos
Autores principales: Maulik, Angshuman, Davidson, Sean M., Piotrowska, Izabela, Walker, Malcolm, Yellon, Derek M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018575/
https://www.ncbi.nlm.nih.gov/pubmed/29766336
http://dx.doi.org/10.1007/s10557-018-6793-y