Cargando…

Ischaemic Preconditioning Protects Cardiomyocytes from Anthracycline-Induced Toxicity via the PI3K Pathway

PURPOSE: Anthracyclines cause chronic irreversible cardiac failure, but the mechanism remains poorly understood. Emerging data indicate that cardiac damage begins early, suggesting protective modalities delivered in the acute stage may confer prolonged benefit. Ischaemic preconditioning (IPC) activa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Maulik, Angshuman, Davidson, Sean M., Piotrowska, Izabela, Walker, Malcolm, Yellon, Derek M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018575/ https://www.ncbi.nlm.nih.gov/pubmed/29766336 http://dx.doi.org/10.1007/s10557-018-6793-y

Ejemplares similares

Anthracycline Chemotherapy and Cardiotoxicity
por: McGowan, John V, et al.
Publicado: (2017)

Role of PI3K in myocardial ischaemic preconditioning: mapping pro‐survival cascades at the trigger phase and at reperfusion
por: Rossello, Xavier, et al.
Publicado: (2017)

Mitochondrial cyclophilin-D as a critical mediator of ischaemic preconditioning
por: Hausenloy, Derek J., et al.
Publicado: (2010)

Ventilation strategy has a major influence on remote ischaemic preconditioning in mice
por: Davidson, Sean M., et al.
Publicado: (2017)

Endothelial cells release cardioprotective exosomes that may contribute to ischaemic preconditioning
por: Davidson, Sean M., et al.
Publicado: (2018)

Effect of Remote Ischaemic Conditioning in Oncology Patients Undergoing Chemotherapy: Rationale and Design of the ERIC‐ONC Study—A Single‐Center, Blinded, Randomized Controlled Trial
por: Chung, Robin, et al.
Publicado: (2016)

From Protecting the Heart to Improving Athletic Performance – the Benefits of Local and Remote Ischaemic Preconditioning
por: Sharma, Vikram, et al.
Publicado: (2015)

Intrinsic cardiac ganglia and acetylcholine are important in the mechanism of ischaemic preconditioning
por: Pickard, J. M. J., et al.
Publicado: (2017)

The Akt1 isoform is an essential mediator of ischaemic preconditioning
por: Kunuthur, Suma P, et al.
Publicado: (2012)

Remote ischaemic preconditioning for coronary artery bypass grafting
por: Benstoem, Carina, et al.
Publicado: (2015)

Remote ischaemic preconditioning ameliorates anthracycline-induced cardiotoxicity and preserves mitochondrial integrity
por: Galán-Arriola, Carlos, et al.
Publicado: (2020)

An investigation into the effects of simulated ischaemic preconditioning on mitochondrial fusion in mouse embryonic fibroblasts
por: Chew, Ernest J, et al.
Publicado: (2015)

Ischaemic Preconditioning and Postconditioning do not Affect Adenosine A(1) and A(2A) Receptor Sensitivity
por: Riksen, Niels P., et al.
Publicado: (2009)

Myocardial Infarct Size Reduction Provided by Local and Remote Ischaemic Preconditioning: References Values from the Hatter Cardiovascular Institute
por: Rossello, Xavier, et al.
Publicado: (2018)

Does remote ischaemic conditioning reduce inflammation? A focus on innate immunity and cytokine response
por: Pearce, Lucie, et al.
Publicado: (2021)

Anthracyclines and Biomarkers of Myocardial Injury: The Effect of Remote Ischemic Conditioning
por: Mallouppas, Michael, et al.
Publicado: (2023)

Therapeutic strategies utilizing SDF-1α in ischaemic cardiomyopathy
por: Ziff, Oliver J, et al.
Publicado: (2018)

Neural mechanisms in remote ischaemic conditioning in the heart and brain: mechanistic and translational aspects
por: Basalay, Marina V., et al.
Publicado: (2018)

The role of PI3Kα isoform in cardioprotection
por: Rossello, Xavier, et al.
Publicado: (2017)

Preconditioning the diabetic human myocardium
por: Sivaraman, Vivek, et al.
Publicado: (2010)

Protection of the ischaemic heart: investigations into the phenomenon of ischaemic preconditioning
por: Lochner, A, et al.
Publicado: (2009)

Remote ischaemic preconditioning: closer to the mechanism?
por: Gleadle, Jonathan M., et al.
Publicado: (2016)

Targeting myocardial ischaemic injury in the absence of reperfusion
por: Basalay, M. V., et al.
Publicado: (2020)

Ischaemic preconditioning and pharmacological preconditioning with dexmedetomidine in an equine model of small intestinal ischaemia-reperfusion
por: König, Kathrin S., et al.
Publicado: (2020)

Does Remote Ischaemic Preconditioning Protect Kidney and Cardiomyocytes After Coronary Revascularization? A Double Blind Controlled Clinical Trial
por: Nouraei, Seyed Mahmoud, et al.
Publicado: (2016)

Molecular Mechanism of Ischaemic Preconditioning of Skeletal Muscle In Vitro
por: Fox, Ciara, et al.
Publicado: (2018)

The impact of acute remote ischaemic preconditioning on cerebrovascular function
por: Carter, Howard H., et al.
Publicado: (2020)

Remote ischaemic preconditioning – translating cardiovascular benefits to humans
por: Lang, James A., et al.
Publicado: (2022)

An Evaluation of Ischaemic Preconditioning as a Method of Reducing Ischaemia Reperfusion Injury in Liver Surgery and Transplantation
por: Robertson, Francis P., et al.
Publicado: (2017)

Remote ischaemic conditioning reduces infarct size in animal in vivo models of ischaemia-reperfusion injury: a systematic review and meta-analysis
por: Bromage, Daniel I., et al.
Publicado: (2017)

Radiotherapy and anthracyclines – cardiovascular toxicity
por: Mozdzanowska, Dagmara, et al.
Publicado: (2014)

Randomised control study of remote ischaemic preconditioning and hepatic function
por: Khan, A, et al.
Publicado: (2013)

Selective protection of human cardiomyocytes from anthracycline cardiotoxicity by small molecule inhibitors of MAP4K4
por: Golforoush, Pelin A., et al.
Publicado: (2020)

STAT5 fits the RISK profile for cardioprotection
por: Davidson, Sean M., et al.
Publicado: (2012)

Exosomes and cardioprotection – A critical analysis
por: Davidson, Sean M., et al.
Publicado: (2018)

Trial of remote ischaemic preconditioning in vascular cognitive impairment (TRIC-VCI): protocol
por: Ganesh, Aravind, et al.
Publicado: (2020)

Protocol for a prospective randomized controlled trial of recipient remote ischaemic preconditioning in orthotopic liver transplantation (RIPCOLT trial)
por: Robertson, Francis P., et al.
Publicado: (2016)

The 10th Biennial Hatter Cardiovascular Institute workshop: cellular protection—evaluating new directions in the setting of myocardial infarction, ischaemic stroke, and cardio-oncology
por: Davidson, Sean M., et al.
Publicado: (2018)

Clinical applications of remote ischaemic preconditioning in native and transplant acute kidney injury
por: Veighey, Kristin, et al.
Publicado: (2014)

Cardioprotection of ischaemic preconditioning is associated with inhibition of translocation of MLKL within the plasma membrane
por: Szobi, Adrián, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_aumneb15f6be92o778f1nbmfrf