Cargando…

l-Phenylalanine Restores Vascular Function in Spontaneously Hypertensive Rats Through Activation of the GCH1-GFRP Complex

Reduced nitric oxide (NO) bioavailability correlates with impaired cardiovascular function. NO is extremely labile and has been challenging to develop as a therapeutic agent. However, NO bioavailability could be enhanced by pharmacologically targeting endogenous NO regulatory pathways. Tetrahydrobio...

Descripción completa

Detalles Bibliográficos
Autores principales: Heikal, Lamia, Starr, Anna, Hussein, Dania, Prieto-Lloret, Jesus, Aaronson, Phil, Dailey, Lea Ann, Nandi, Manasi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018612/
https://www.ncbi.nlm.nih.gov/pubmed/29963647
http://dx.doi.org/10.1016/j.jacbts.2018.01.015