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l-Phenylalanine Restores Vascular Function in Spontaneously Hypertensive Rats Through Activation of the GCH1-GFRP Complex

Reduced nitric oxide (NO) bioavailability correlates with impaired cardiovascular function. NO is extremely labile and has been challenging to develop as a therapeutic agent. However, NO bioavailability could be enhanced by pharmacologically targeting endogenous NO regulatory pathways. Tetrahydrobio...

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Detalles Bibliográficos
Autores principales:	Heikal, Lamia, Starr, Anna, Hussein, Dania, Prieto-Lloret, Jesus, Aaronson, Phil, Dailey, Lea Ann, Nandi, Manasi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	PRECLINICAL RESEARCH
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018612/ https://www.ncbi.nlm.nih.gov/pubmed/29963647 http://dx.doi.org/10.1016/j.jacbts.2018.01.015

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