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Characterization of designed, synthetically accessible bryostatin analog HIV latency reversing agents
HIV latency in resting CD4+ T cell represents a key barrier preventing cure of the infection with antiretroviral drugs alone. Latency reversing agents (LRAs) can activate HIV expression in latently infected cells, potentially leading to their elimination through virus-mediated cytopathic effects, ho...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018613/ https://www.ncbi.nlm.nih.gov/pubmed/29800728 http://dx.doi.org/10.1016/j.virol.2018.05.006 |