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Improved identification of concordant and discordant gene expression signatures using an updated rank-rank hypergeometric overlap approach
Recent advances in large-scale gene expression profiling necessitate concurrent development of biostatistical approaches to reveal meaningful biological relationships. Most analyses rely on significance thresholds for identifying differentially expressed genes. We use an approach to compare gene exp...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018631/ https://www.ncbi.nlm.nih.gov/pubmed/29942049 http://dx.doi.org/10.1038/s41598-018-27903-2 |