Cargando…

Mutually exclusive acetylation and ubiquitylation of the splicing factor SRSF5 control tumor growth

Most tumor cells take up more glucose than normal cells. Splicing dysregulation is one of the molecular hallmarks of cancer. However, the role of splicing factor in glucose metabolism and tumor development remains poorly defined. Here, we show that upon glucose intake, the splicing factor SRSF5 is s...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yuhan, Huang, Qingyang, Liu, Wen, Zhu, Qiong, Cui, Chun-Ping, Xu, Liang, Guo, Xing, Wang, Ping, Liu, Jingwen, Dong, Guanglong, Wei, Wenyi, Liu, Cui Hua, Feng, Zhichun, He, Fuchu, Zhang, Lingqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018636/
https://www.ncbi.nlm.nih.gov/pubmed/29942010
http://dx.doi.org/10.1038/s41467-018-04815-3