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Mutually exclusive acetylation and ubiquitylation of the splicing factor SRSF5 control tumor growth
Most tumor cells take up more glucose than normal cells. Splicing dysregulation is one of the molecular hallmarks of cancer. However, the role of splicing factor in glucose metabolism and tumor development remains poorly defined. Here, we show that upon glucose intake, the splicing factor SRSF5 is s...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018636/ https://www.ncbi.nlm.nih.gov/pubmed/29942010 http://dx.doi.org/10.1038/s41467-018-04815-3 |