TP53 protein levels, RNA-based pathway assessment, and race among invasive breast cancer cases

Mutations in tumor suppressor TP53 have been inconsistently linked to breast cancer risk factors and survival. Immunohistochemistry (IHC) staining, a primary clinical means of TP53 mutation determination, only detects mutations that facilitate protein accumulation (e.g., missense mutations). RNA-bas...

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Detalles Bibliográficos
Autores principales: Williams, Lindsay A., Butler, Ebonee N., Sun, Xuezheng, Allott, Emma H., Cohen, Stephanie M., Fuller, Ashley M., Hoadley, Katherine A., Perou, Charles M., Geradts, Joseph, Olshan, Andrew F., Troester, Melissa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018637/
https://www.ncbi.nlm.nih.gov/pubmed/29951581
http://dx.doi.org/10.1038/s41523-018-0067-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018637/
https://www.ncbi.nlm.nih.gov/pubmed/29951581
http://dx.doi.org/10.1038/s41523-018-0067-5

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