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Paracrine effect of regulatory T cells promotes cardiomyocyte proliferation during pregnancy and after myocardial infarction

Cardiomyocyte proliferation stops at birth when the heart is no longer exposed to maternal blood and, likewise, to regulatory T cells (Tregs) that are expanded to promote maternal tolerance towards the fetus. Here, we report a role of Tregs in promoting cardiomyocyte proliferation. Treg-conditioned...

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Detalles Bibliográficos
Autores principales: Zacchigna, Serena, Martinelli, Valentina, Moimas, Silvia, Colliva, Andrea, Anzini, Marco, Nordio, Andrea, Costa, Alessia, Rehman, Michael, Vodret, Simone, Pierro, Cristina, Colussi, Giulia, Zentilin, Lorena, Gutierrez, Maria Ines, Dirkx, Ellen, Long, Carlin, Sinagra, Gianfranco, Klatzmann, David, Giacca, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018668/
https://www.ncbi.nlm.nih.gov/pubmed/29946151
http://dx.doi.org/10.1038/s41467-018-04908-z