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Characterization of migratory primordial germ cells in the aorta-gonad-mesonephros of a 4.5-week-old human embryo: a toolbox to evaluate in vitro early gametogenesis

STUDY QUESTION: Which set of antibodies can be used to identify migratory and early post-migratory human primordial germ cells (hPGCs)? STUDY FINDING: We validated the specificity of 33 antibodies for 31 markers, including POU5F1, NANOG, PRDM1 and TFAP2C as specific markers of hPGCs at 4.5 weeks of...

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Detalles Bibliográficos
Autores principales: Gomes Fernandes, Maria, Bialecka, Monika, Salvatori, Daniela C F, Chuva de Sousa Lopes, Susana M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018722/
https://www.ncbi.nlm.nih.gov/pubmed/29528446
http://dx.doi.org/10.1093/molehr/gay011