Data-driven approaches used for compound library design, hit triage and bioactivity modeling in high-throughput screening

High-throughput screening (HTS) campaigns are routinely performed in pharmaceutical companies to explore activity profiles of chemical libraries for the identification of promising candidates for further investigation. With the aim of improving hit rates in these campaigns, data-driven approaches ha...

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Detalles Bibliográficos
Autores principales: Paricharak, Shardul, Méndez-Lucio, Oscar, Chavan Ravindranath, Aakash, Bender, Andreas, IJzerman, Adriaan P, van Westen, Gerard J P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018726/
https://www.ncbi.nlm.nih.gov/pubmed/27789427
http://dx.doi.org/10.1093/bib/bbw105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018726/
https://www.ncbi.nlm.nih.gov/pubmed/27789427
http://dx.doi.org/10.1093/bib/bbw105

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