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Selection of validated hypervariable regions is crucial in 16S-based microbiota studies of the female genital tract
Next-generation sequencing-based methods are extensively applied in studies of the human microbiota using partial 16 S rRNA gene amplicons. However, they carry drawbacks that are critical to consider when interpreting results, including differences in outcome based on the hypervariable region(s) use...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018735/ https://www.ncbi.nlm.nih.gov/pubmed/29946153 http://dx.doi.org/10.1038/s41598-018-27757-8 |