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Double Strand Break DNA Repair occurs via Non-Homologous End-Joining in Mouse MII Oocytes

The unique biology of the oocyte means that accepted paradigms for DNA repair and protection are not of direct relevance to the female gamete. Instead, preservation of the integrity of the maternal genome depends on endogenous protein stores and/or mRNA transcripts accumulated during oogenesis. The...

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Detalles Bibliográficos
Autores principales: Martin, Jacinta H., Bromfield, Elizabeth G., Aitken, R. John, Lord, Tessa, Nixon, Brett
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018751/
https://www.ncbi.nlm.nih.gov/pubmed/29946146
http://dx.doi.org/10.1038/s41598-018-27892-2