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Both cardiomyocyte and endothelial cell Nox4 mediate protection against hemodynamic overload-induced remodelling
AIMS: NADPH oxidase-4 (Nox4) is an important reactive oxygen species (ROS) source that is upregulated in the haemodynamically overloaded heart. Our previous studies using global Nox4 knockout (Nox4KO) mice demonstrated a protective role of Nox4 during chronic abdominal aortic banding, involving a pa...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018755/ https://www.ncbi.nlm.nih.gov/pubmed/29040462 http://dx.doi.org/10.1093/cvr/cvx204 |