Both cardiomyocyte and endothelial cell Nox4 mediate protection against hemodynamic overload-induced remodelling

AIMS: NADPH oxidase-4 (Nox4) is an important reactive oxygen species (ROS) source that is upregulated in the haemodynamically overloaded heart. Our previous studies using global Nox4 knockout (Nox4KO) mice demonstrated a protective role of Nox4 during chronic abdominal aortic banding, involving a pa...

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Detalles Bibliográficos
Autores principales: Zhang, Min, Mongue-Din, Heloise, Martin, Daniel, Catibog, Norman, Smyrnias, Ioannis, Zhang, Xiaohong, Yu, Bin, Wang, Minshu, Brandes, Ralf P, Schröder, Katrin, Shah, Ajay M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018755/
https://www.ncbi.nlm.nih.gov/pubmed/29040462
http://dx.doi.org/10.1093/cvr/cvx204

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