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An in vitro potency assay using nicotinic acetylcholine receptor binding works well with antivenoms against Bungarus candidus and Naja naja

In order to facilitate/expedite the production of effective and affordable snake antivenoms, a novel in vitro potency assay was previously developed. The assay is based on an antiserum’s ability to bind to postsynaptic neurotoxin (PSNT) and thereby inhibit the PSNT binding to the nicotinic acetylcho...

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Detalles Bibliográficos
Autores principales: Ratanabanangkoon, Kavi, Simsiriwong, Pavinee, Pruksaphon, Kritsada, Tan, Kae Yi, Chantrathonkul, Bunkuea, Eursakun, Sukanya, Tan, Choo Hock
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018763/
https://www.ncbi.nlm.nih.gov/pubmed/29946111
http://dx.doi.org/10.1038/s41598-018-27794-3