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Pulmonary Arterial Hypertension Affects the Rat Gut Microbiome

We have analysed whether pulmonary arterial hypertension (PAH) alters the rat faecal microbiota. Wistar rats were injected with the VEGF receptor antagonist SU5416 (20 mg/kg s.c.) and followed for 2 weeks kept in hypoxia (10% O(2), PAH) or injected with vehicle and kept in normoxia (controls). Faeca...

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Detalles Bibliográficos
Autores principales: Callejo, María, Mondejar-Parreño, Gema, Barreira, Bianca, Izquierdo-Garcia, José L., Morales-Cano, Daniel, Esquivel-Ruiz, Sergio, Moreno, Laura, Cogolludo, Ángel, Duarte, Juan, Perez-Vizcaino, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018770/
https://www.ncbi.nlm.nih.gov/pubmed/29946072
http://dx.doi.org/10.1038/s41598-018-27682-w