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Warfarin maintenance dose Prediction for Patients undergoing heart valve replacement— a hybrid model with genetic algorithm and Back-Propagation neural network
Warfarin is the most recommended anticoagulant drug for patients undergoing heart valve replacement. However, due to the narrow therapeutic window and individual dose, the use of warfarin needs more advanced technology. We used the data collected from a multi-central registered clinical system all o...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018790/ https://www.ncbi.nlm.nih.gov/pubmed/29946101 http://dx.doi.org/10.1038/s41598-018-27772-9 |