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Elevated circulating levels of succinate in human obesity are linked to specific gut microbiota

Gut microbiota-related metabolites are potential clinical biomarkers for cardiovascular disease (CVD). Circulating succinate, a metabolite produced by both microbiota and the host, is increased in hypertension, ischemic heart disease, and type 2 diabetes. We aimed to analyze systemic levels of succi...

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Detalles Bibliográficos
Autores principales: Serena, Carolina, Ceperuelo-Mallafré, Victoria, Keiran, Noelia, Queipo-Ortuño, Maria Isabel, Bernal, Rosa, Gomez-Huelgas, Ricardo, Urpi-Sarda, Mireia, Sabater, Mónica, Pérez-Brocal, Vicente, Andrés-Lacueva, Cristina, Moya, Andres, Tinahones, Francisco J, Fernández-Real, Jose Manuel, Vendrell, Joan, Fernández-Veledo, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018807/
https://www.ncbi.nlm.nih.gov/pubmed/29434314
http://dx.doi.org/10.1038/s41396-018-0068-2