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lincROR influences the stemness and crizotinib resistance in EML–ALK(+) non-small-cell lung cancer cells

INTRODUCTION: Echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4–ALK) is identified as an important pathogenic factor in patients with non-small-cell lung cancer (NSCLC) and could induce a stem-like phenotype in NSCLC cells. Crizotinib is commonly used for EML4–ALK(+)...

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Detalles Bibliográficos
Autores principales: Yang, Yonghua, Huang, Jingyu, Xie, Nianlin, Huang, Hu, Xu, Shaogan, Cai, Jun, Qi, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018841/
https://www.ncbi.nlm.nih.gov/pubmed/29950868
http://dx.doi.org/10.2147/OTT.S165290